have a digenetic lifestyle cycle, involving a motile, extracellular promastigote phase that parasitizes the alimentary tract of a sandfly vector and an immotile amastigote stage that survives and replicates while in the phagolysosomes of mononuclear phagocytes [2,3]. Apart from individuals, Principal hosts of Leishmania, et al CDK12 inhibition reve
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